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arob.base.eth🍖🎩 pfp
arob.base.eth🍖🎩
@arob1000
I'm currently developing T-Cell Engagers for solid tumors. They are "eat me" signals that attach to cancer cells kill them. It is a very simple concept but can easily kill someone if they bind to normal cells. We make T-Cell Engagers that are inactive until they get to the tumor, reducing toxicity.
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@om3ga3v3
how do you ensure that the t cell engagers remain inactive until they reach target? is this type of treatment available to everyone, or is it still being tested?
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arob.base.eth🍖🎩 pfp
arob.base.eth🍖🎩
@arob1000
Still in clinical trials. Great question, proteases involved in cancer progression activate the drug, without those proteases and cancer cells it is inactive.
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