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arob.base.eth pfp
arob.base.eth
@arob1000
I'm currently developing T-Cell Engagers for solid tumors. They are "eat me" signals that attach to cancer cells kill them. It is a very simple concept but can easily kill someone if they bind to normal cells. We make T-Cell Engagers that are inactive until they get to the tumor, reducing toxicity.
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@jj
Pretty cool my wife is working on using NK version of CART because CART can be risky where you need T donors or your own T cells because of graft vs host
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arob.base.eth pfp
arob.base.eth
@arob1000
Very cool, similar concept but CART requires a lot of engineering, I was super excited about allogenic CART’s but they haven’t done much in solid tumors so far. T Cell Engagers appear to be working so far 🀞
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