Science
Looking at the world as it is, unencumbered by how we want it to be. Proudly hosted by @aviationdoctor.eth and co-modded by @eulerlagrange.eth @gmo @johncamkiran
Monteluna pfp

@monteluna

Subnautica technology but for planet Earth. Who's building this? https://youtu.be/59xmMu0BMzc?si=7zrTD4VwrWq8eIus
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Alfie pfp

@alfie

Just taking a second to acknowledge some of the crazy advances made in bio in Jan as well as the Steel paper: new DNA assembly method that made $twist pump: https://doi.org/10.1038/s41586-025-10006-0 Alphagenome: https://doi.org/10.1038/s41586-025-10014-0 Also, why did George Church visit Epstein’s island 💀
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FailsBothProngsLagrange pfp

@eulerlagrange.eth

I just realized that the first Artemis launch is scheduled for March of this year. This will send humans the furthest away from Earth ever, with the planned boots on lunar soil for 2027. Bruh I remember hearing this back in like high school and it’s finally happening.
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Thomas pfp

@aviationdoctor.eth

I’m glad that Curt Jaimungal has been releasing multiple interviews of Roger Penrose lately, including on consciousness. The man’s a civilizational treasure and arguably one of, if not the brightest scientific minds still alive. We need to capture and document as many of his thoughts while we still can
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Alfie pfp

@alfie

Few things in molecular biology as satisfying as gel electrophoresis. This is a method that separates dna based on its length by applying a current to an agarose del with dyed DNA. Please excuse my 3x coffee shakey hands😂
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kevin j pfp

@entropybender

cursor for overleaf
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Alfie pfp

@alfie

In science it’s a rat race to be the first person to do something. On that note, bet I’m the only person in the world to have listened to Tim Reaper while reading about engineering magneto sensitive proteins as quantum sensors. Mix and DOI below so protocol can be reproduced x https://on.soundcloud.com/idr6Um0cZAfG8t6ePM https://doi.org/10.1038/s41586-025-09971-3
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Alfie pfp

@alfie

Reminder to have fun with it
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Alfie pfp

@alfie

Round 1 of Live Sciences begins next week. No narrative spinning, no negative data brushed under carpet, just raw data live streamed online from this bioreactor. Anyone can interact anyone can analyse.
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Thomas pfp

@aviationdoctor.eth

Analogies are indispensable to communicating scientific concepts foreign to a given audience. But analogies never map 1:1 to the territory. They are only analogous to the real phenomenon in some specific ways (corresponding to the science communicator’s intent), and not in others. Yet, audiences are prone to extrapolating analogies in unpredictable ways that no longer apply to the phenomenon. If the science communicator now repudiates the analogy, it confuses the audience; if they don’t, it leaves the audience with an objectively wrong mental model. Sean Carroll uses the example of inflating a balloon to model the Big Bang. It correctly shows spacetime itself (the balloon’s surface) stretching, stars drawn on the surface moving apart without any obvious center of expansion, and distant stars moving away even faster (Hubble’s law). But anyone taking the analogy too literally will also see stars getting larger, the balloon expanding *into* some external volume, and spacetime being 2D. All of which are not analogous to cosmic inflation. So a skilled science communicator must not only use audience-appropriate analogies (by age, level of knowledge, domain of competence, etc), but also be very clear about the specific ways in which the analogy applies to the real world
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Drew Volpe pfp

@drew

Recap of medical breakthroughs of 2025: * A baby named KJ became the first gene-edited baby, and the first person to be treated with a custom in vivo CRISPR treatment for his rare genetic disease * A research team at Roche and Boston’s Children’s Hospital set a new world record for the fastest human genome sequencing and analysis: under 4 hours to perform whole genome sequencing and analysis * Roche developed a new genome sequencing method called Sequencing by Expansion (SBX), which expands DNA molecules into larger structures called Xpandomers * Suzetrigine became the first non-opioid painkiller for surgical treatment in decades * The second chikungunya vaccine was approved in the US and EU * Several new lipid-lowering treatments are succeeding in large clinical trials * Orforglipron is a new GLP1 drug that can be taken orally https://www.scientificdiscovery.dev/p/medical-breakthroughs-in-2025
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eatzebugs pfp

@eatzebugs

https://www.youtube.com/watch?v=UoSs5ihTZNQ where is it going to hit, farcaster?
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Monteluna pfp

@monteluna

There needs to be a rule that entrepreneurs must consult with someone who has at least passed a few physics courses. So I'm supposed pay $1800 to stand out in the cold wind during a thunderstorm and larp as a human lightning rod, and I guess I'll lose so much heat so when the lightning does strike me, I guess I won't feel anything? https://vollebak.com/en-us/products/full-metal-jacket-copper-edition
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FailsBothProngsLagrange pfp

@eulerlagrange.eth

https://youtu.be/ZXNIgHov0Nk?si=YtJwK8gNmPBksRqZ
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zoo pfp

@zoo

if cells can do it, why cant we? https://x.com/profbuehlermit/status/2002264253613445491?s=46&t=Il5NrMeCjY0zjgXBkcDWtA
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