Pretty cool. researchers isoLated 22 antimicrobial peptides (AMPs) from the skin mucus of the axolotl (didnt even though this creature existed) as part of finding antibiotic alternatives amid rising drug resistance. 

Four of these AMPs potently inhibited both methicillin-resistant (MRSA) and methicillin-sensitive Staphylococcus aureus, and three simultaneously triggered apoptosis in a type of breast-cancer cells while shifting gene expression toward tumor suppression. 
 
An interesting result from the breast cancer aspect is the decreased IL-6 levels (last slide below) with > 2-fold down-regulation of IL-6 mRNA in T-47D breast-cancer cells after 24 h exposure to peptides 1, 12,13. We could extract value from this into other inflammatory issues that are cytokine mediated (since thats where IL-6 only reduction has the most impact). Also they're baby preferred creatures!

Physician always trying to learn, passionate about healthspan and precision medicine.

omarsaleem.xyz

Wow that's amazing, axolotl mucus could help fight superbugs and cancer while being adorable little creatures, science is so cool