Global economic uncertainty, such as inflation and interest rate changes, impacts cryptocurrency markets in several ways:

1. **Inflation Hedge**: Bitcoin and crypto are often seen as hedges against inflation, driving demand during high inflation periods.  
2. **Interest Rates**: Rising rates may reduce risk appetite, leading to sell-offs in volatile assets like crypto.  
3. **Investor Sentiment**: Economic instability can push investors toward safe havens or alternative assets, influencing crypto prices.  
4. **Currency Devaluation**: Weak fiat currencies may increase crypto adoption as a store of value.  

These factors create a complex interplay, making crypto markets highly reactive to macroeconomic shifts.