This baby was the world's first ever healed with a personalized gene editing treatment https://www.nytimes.com/2025/05/15/health/gene-editing-personalized-rare-disorders.html

BEFORE
"KJ’s disease is caused by an inability to rid the body of ammonia, a byproduct of protein metabolism. Ammonia builds up in the blood and crosses into the brain. His doctors put him on a diet that severely restricted protein — just enough for him to grow. He also had a medicine that helped remove the ammonia in his blood. But he still was at high risk for brain injury or death. Any illness could make his ammonia levels soar and cause irreversible damage to his brain."

AFTER
"It is too soon to know if he can stop taking the medication completely, but the dosage is greatly reduced. And he is well enough for the team to start planning to discharge him home from the hospital. He is meeting milestones and his weight is now in the 40th percentile for his age, but it is not yet known if he’ll be spared a liver transplant."

Oftentimes it feels like the technological leaps of our age are solutions in search of problems, mostly designed to undercut the working man on behalf of the monied class or harvest more precious attention for profit. 

Then you see stuff like this.

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I am always interested in these stories because I have a genetic mutation that threatens me on a longer time horizon, and despite the positivity from stories like this I also do not believe any solution like this will ever be within my reach unless I become a billionaire

While its easiest to give into nihilism, its almost always the wrong response. We live in the best time ever for humanity and its getting better. So happy this little guy is doing well!

CRISPR is an amazing biotech. I attended a presentation by Dr. Doudna here in Berkeley detailing her invention in 2019(?).

Last week, I saw a report of a woman whose cancer was cured by editing, growing, and injecting the messenger part that identifies a cancer cell so white blood cells can kill them.

Amazing 🤩