@bli.eth

🧠 Improvements in compute and novel AI models - AI reduces the barrier to entry for startups in capital intensive industries like pharma where they can bring the cost of developing viable drug candidates from $1b to tens of millions. Pharma companies are willing to commit to large contracts and foot the R&D bill of these startups for the potential payoffs. - Powerful foundational models like AlphaFold are now capable of generating viable synthetic data for training new models, creating an explosion in training data that can be purchased at affordable prices. - New models like o1 with advanced reasoning capabilities can synthesize complex scientific papers/concepts, making it easier for motivated founders to gain the technical knowledge needed for hard-tech. - AI is creating massive new demand for energy and chips that outstrips supply, creating market opportunities for profit and innovation in industries that had previously been relatively competitive and commoditized.

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