Professor of Biochemistry and Associate Editor at ResearchHub
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I just funded: Identifying exposome drivers of age-associated low-grade inflammation on ResearchHub! https://www.researchhub.com/fund/4528/identifying-exposome-drivers-of-age-associated-low-grade-inflammation/conversation?utm_source=x&utm_medium=social_share
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I just donated to @lorah24's crowdfund "Help me get back to school"
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Interesting stuff: here's your chance to bet on a replication study. https://x.com/DeSciNews/status/1986569314091344092?s=20
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Here's a exciting new preprint on the generative design of peptides to disrupt protein–protein interactions. Anyone with expertise can submit a public peer review on ResearchHub and earn $150 in RSC (now on Coinbase!). Review bounty: https://www.researchhub.com/paper/9460598/generative-design-of-high-affinity-peptides-using-bindcraft/bounties
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Just published a new @researchhub Journal paper on how different DNA polymerase peptides compete for the Mycobacterial β‑clamp. X‑ray crystal structures plus binding assays reveal how clamp‑binding motifs drive polymerase recruitment.
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I used Biomni Co-Pilot to fit data for the first time (until today I've only used it for construct design and background research). I was super impressed. It was simple peptide binding data, but it did the fitting, made the plots, and gave me a nice text summary in less than 5 minutes. I do this type of analysis all the time and it would have probably taken me 15 minutes if I didn't get interrupted by anything. If you are interested, you can see the output at the very bottom of this research notebook: I'm looking forward to giving it more complex data soon.