Omar (dromar.eth)

Omar

Physician always trying to learn, passionate about healthspan and precision medicine. omarsaleem.xyz

886 Followers

Recent casts

California doesnt have school buses. after school pickup is navgating nearly 100s of teenagers riding down in e-bikes

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Have had 3 e-bike trauma cases this past month. All under 45yo. 1 lost a leg 1 punctured a lung with shattered ribs 1 got hit by a F350 Something has to be done with these.

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South Asians are often told their BMI is “normal”...an incomplete metric. The better question is: where did the fat go? For many of us, surplus fat shows up earlier in the liver, pancreas, muscle, heart, and kidney. That’s the Overflow Tank. Ectopic fat is the medical term, and we dive deep into it this week. New post: https://open.substack.com/pub/grasshoppermed/p/the-overflow-tank-on-ectopic-fat?r=1fp8g&utm_medium=ios

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Top casts

If anyone is looking for an amazing and accurate body measurement tool then would recommend Renpho. Much more accurate and precise than In-body imo and used by more and more researchers now. It’s as close to a Dexa as you can get and much less expensive/can do it at home. https://amzn.to/3K5R78g

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Had a patient today with pretty bad sepsis, bed bound from stroke with parkinson dementia. His wife is also walker bound with early dementia. Son takes care of both of them, works from home. Nice to see that in our individualistic society these days. Met a hero today.

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Big news today: GLP-1 shortage is over. This will have big implications for compounding pharmacies, patients but much much more Essentially, FDA declared not that Ozempic/Wegovy (semaglutide) shortage resolved, meaning compounded GLP-1s are no longer allowed, tanked HIMS stock. For perspective, ~25% of GLP-1s are compounded, serving millions of patients. And a big source of revenue for compounders that have shifted biz models, but even more so developed these into robust treatments (ex: B12/sema combo) Compounders are now challenging in court to continue production, tirzepatide is already in court, semaglutide cases likely will join in. During this time, while the current lawsuit ongoing, FDA is maintaining its enforcement discretion. Now here is where this turns another corner:

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Feels like in this productivity-obsessed world, conversations about literature—sci-fi, hidden classics, all of it—are getting harder to find. Strange how we sideline what sparks imagination for what just optimizes time. Boredom has become a scarcity.

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